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| Product Name | Follistatin, Recombinant, Human (FS, Activin-Binding Protein, FST) |
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| Description | Purity ~95% (SDS-PAGE). Expressed in the pituitary, ovaries, and in some other tissues, FST is a high affinity activin binding protein that can act as an activin antagonist. FST was originally discovered through its suppressive effect of the expression and secretion of the pituitary follicle stimulating hormone. Besides activin, FS has also been shown to bind with multiple BMPs, Myostatin, GDF-11, and TGF-beta-1. Human Follistatin contains three cysteine-rich domains (called Follistatin-like domains), 3 Kazal-like domains and one TGF-beta binding domain. Source: Recombinant protein corresponding to human Follistatin expressed in E. coli. Molecular Weight: ~31kD Biological Activity: The ED50 was determined by the ability to neutralize Activin A inhibitory effect of mouse MPC-11 cells and was 0.1-0.4ug/mL in the presence of 7.5ng/ml Activin A. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: P19883 |
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| Catalog # | 500022 |
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| Order / More Info | Follistatin, Recombinant, Human (FS, Activin-Binding Protein, FST) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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