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| Product Name | Follistatin, Recombinant, Mouse (FS, FST, Activin-Binding Protein, FSH-Suppressing Protein, FSP) |
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| Description | Purity ~90% (SDS-PAGE, HPLC). Follistatin is an autocrine acting protein that is expressed by many tissues, but at noteably higher levels in the ovary and skin. Follistatin functions to negatively regulate the signaling of a wide variety of TGF-beta family members (activin, BMPs, myostatin, GDF-11 and TGF-beta 1). Mechanistically, follistatin works as an antagonist by complexing with TGF-beta family members to prevent them from interacting with their signaling receptors. Source: Recombinant protein corresponding to 289aa from mouse Follistatin, expressed in E. coli. Molecular Weight: ~31.6kD Biological Activity: Determined by the dose-dependent neutralization of 7.5ng/ml human Activin A. Complete neutralization is typically reached at <0.3ug/ml. Endotoxin: <0.1EU/ug purified protein AA Sequence: MGNCWLRQAK NGRCQVLTKT ELSKEECCST GRLSTSWTEE DVNDNTLFKW MIFNGGAPNC IPCKETCENV DCGPGKKCRM NKKNKPRCVC APDCSNITWK GPVCGLDGKT YRNECALLKA RCKEQPELEV QYQGRCKKTC RDVFCPGSST CVVDQTNNAY CVTCNRICPE PASSEQ |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | FS, activin-binding protein, FSH-suppressing protein (FSP) |
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| Gene, Accession, CAS # | FST, Gene ID: 14313, SwissProt: P47931 |
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| Catalog # | 219774 |
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| Order / More Info | Follistatin, Recombinant, Mouse (FS, FST, Activin-Binding Protein, FSH-Suppressing Protein, FSP) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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