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| Product Name | Human IL-13 alpha 2 receptor Recombinant (IL13RA2) |
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| Description | MW: 44,176 Da. Purity >98%, as determined by SDS-PAGE and HPLC. The biological activity of IL-13 is regulated via the IL-13R type I and type II. The type I receptor is a heterodimer of the IL-4R α chain (IL-4Rα) and IL-13Rα1, and ligand-receptor interactions induce phosphorylation of the IL- 4Rα and subsequent activation of the signal transducers and activators of transcription (STAT) -6 signaling pathway. This pathway appears to be the primary pathway for IL-13- induced sign |
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| Size | 0.02 mg, 0.1 mg, 0.5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Human IL-13 alpha 2 receptor Recombinant; IL13RA2; IL-13RA2; CD213] |
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| Gene, Accession, CAS # | IL13RA2, Gene ID: 3598, Accession: NP_000631.1 |
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| Catalog # | MBS553247 |
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| Order / More Info | Human IL-13 alpha 2 receptor Recombinant (IL13RA2) from MYBIOSOURCE INC. |
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| Product Specific References | • IL-13R2 has a protective role in a mouse model of cutaneous inflammation .J. Immunol., Dec 2010; 185: 6802 - 6808. • IL-13R2 membrane and soluble isoforms differ in humans and mice .J. Immunol., Dec 2009; 183: 7870 - 7876. • tuning sensitivity to il-4 and il-13: differential expression of il-4r, IL-13R1, and c regulates relative cytokine sensitivity .J. Exp. Med., Oct 2008; 205: 2595 - 2608. • novel role of il-13 in fibrosis induced by nonalcoholic steatohepatitis and its a |
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