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Product Name | Interleukin 15 (IL15) (Active) protein |
Description | Human Interleukin 15 (IL-15) is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 binds to the alpha subunit of the IL15 receptor (IL-15RA) with high affinity. IL-15 also binds to the beta and gamma chains of the IL-2 receptor, but not the alpha subunit of the IL2 receptor. IL-15 is structurally and functionally related to IL-2. Both cytokines share some subunits of receptors, allowing them to compete for and negatively regulate each other's activity. The number of CD8+ memory T cells is controlled by a balance between IL-15 and IL-2. Despite their many overlapping functional properties, IL-2 and IL-15 are, in fact, quite distinct players in the immune system. IL-15 is constitutively expressed by a wide variety of cell types and tissues, including monocytes, macrophages and DCs. Mature Human IL-15 shares 70% amino acid sequence identity with Mouse and Rat IL-15.Alternative Names: Interleukin-15, IL-15, IL15 |
Size | 10 µg |
Concentration | n/a |
Applications | n/a |
Other Names | IL15|AI503618|IL-15 |
Gene, Accession, CAS # | Gene ID: 3600 |
Catalog # | ABIN1096896 |
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Order / More Info | Interleukin 15 (IL15) (Active) protein from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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