| 产品详情 |
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| Product Name | AS 604850 |
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| Description | Purity >98% by HPLC. Cell-permeable. A selective, ATP-competitive inhibitor of PI3KGamma with IC50 values of 0.25, >20, >20, and 4.5 µM for the human recombinant Gamma, d, Beta, and a isoforms, respectively. AS 604850 inhibits MCP-1-mediated monocyte chemotaxis with an IC50 value of 21 µM and reduces RANTES-induced peritoneal neutrophil recruitment in a murine model of leukocyte chemotaxis with an ED50 value of 42.4 mg/kg. A selective, ATP-competitive inhibitor of PI3KGamma. (Biochemical) |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5-(2,2-Difluoro-benzo[1,3]dioxol-5-ylmethylene)-thiazolidine-2,4-dione |
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| Gene, Accession, CAS # | CAS: 648449-76-7 |
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| Catalog # | LS-H2917 |
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| Order / More Info | AS 604850 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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