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| Product Name | GFAP, Blocking Protein (Glial Fibrillary Acidic Protein) |
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| Description | Serum. Blocking Protein for G2032-27J. Human GFAP is a 49.7kD protein (432aa) expressed in astrocytes. GFAP is an intermediate filament protein and acts as an intracellular structural component of the cytoskeleton. During embryonic and fetal life, GFAP is also expressed by radial glial cells of the CNS. Various mutations of the GFAP gene in humans produce Alexander's disease, one of the leukodystrophies. Antibodies to GFAP are therefore very useful as markers of astrocytic cells and neural stem cells. In addition many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. Source: Purified Bovine GFAP protein AA Sequence: MERRRVTSATRRSYVSSSEMVVGGRRLGPG TRLSLARMPP PLPARVDFSLAGALNSGFKETRASERAEMM ELNDRFASYI EKVRFLEQQN KALAAELNQLRAKEPTKLAD VYQAELRELR LRLDQLTANS ARLEVERDNL AQDLGTLRQK LQDETNQRLE AENNLAAYRQ EADEATLARLDLERKIESLE EEIRFLRKIH EEEVRELQEQ LAQQQVHVEM DVAKPDLTAALREIRTQYEA VASSNMHEAE EWYRSKFADL NDAAARNAELLRQAKHEAND YRRQLQALTC DLESLRGTNESLERQMREQE ERHAREAA |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 136900 |
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| Order / More Info | GFAP, Blocking Protein (Glial Fibrillary Acidic Protein) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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