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| Product Name | Mouse Gremlin-1 |
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| Description | MW: 20.7 kDa. Purity >95% by SDS-PAGE & silver stain. d cells. Gremlin/Drm belongs to the DAN family of secreted glycoproteins that are BMP antagonists. Other members of the family include: Cerberus, Dante, PRDC, Caronte and DAN. DAN family members share a cysteine-rich domain that is structurally related to the cysteine-knot motif found in TGFbeta superfamily ligands. In vitro, Gremlin/Drm binds BMP4 and BMP2 indicating that it might interfere with BMP signaling. Gremlin/Drm acts as a BMP2/ 4 a |
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| Size | 0.05 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Recombinant Mouse Gremlin-1; Cell proliferation-inducing gene 2 protein; BMP antagonist 1] |
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| Gene, Accession, CAS # | Grem1; Grem1; ld; Drm; Grem; Cktsf1b1; Cktsf1b1; Drm, Gene ID: 23892, Accession: NP_035954.1 |
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| Catalog # | MBS692046 |
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| Order / More Info | Mouse Gremlin-1 from MYBIOSOURCE INC. |
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| Product Specific References | 1. Hsu DR et al, Mol Cell 1 (1998) 2. Merino R et al, Development 126 (1999) 3. Shi W et al, Am J Physiol 280 (2001) 4. Topol LZ et al, JBC 275 (2000). |
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