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| Product Name | CAMKK1, Recombinant, Human, GST-Tag (Calcium/Calmodulin-dependent Protein Kinase Kinase 1, CAMKKA, MGC34095) |
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| Description | Purified (~70-90%). CAMKK1 or CAMKKa is a Ca(2+)/calmodulin-dependent protein kinase that activates CaM-kinases I and IV via phosphorylation of their Thr(177) and Thr(196) residues, respectively. Recent studies have shown that the activity of CAMKK1 is decreased upon phosphorylation by cAMP-dependent protein kinase (PKA) The CAMKKalpha has been identified in intact cells as AMPKKs, predicting a significant role for this kinase in regulating AMPK activity in vivo. It has been shown that 2-deoxyglucose- and ionomycin-stimulated AMPK activity is substantially reduced in HeLa cells transfected with small interfering RNAs specific for CAMKKa. Source: Recombinant protein corresponding to human CAMKK1, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~94kD Specific Activity: 10nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_032294 |
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| Catalog # | 499847 |
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| Order / More Info | CAMKK1, Recombinant, Human, GST-Tag (Calcium/Calmodulin-dependent Protein Kinase Kinase 1, CAMKKA, MGC34095) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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