| 产品详情 |
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| Product Name | RTA 408 |
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| Description | Purity >98%. RTA 408 is a synthetic triterpenoid that binds Keap1 and attenuates the degradation of Nrf2 at concentrations =25 nM. In this way, it suppresses the generation of nitric oxide and pro-inflammatory cytokines in macrophages stimulated with IFN-Gamma. At higher concentrations, RTA 408 inhibits tumor cell growth (GI50 = 260 nM), blocks NF-?B signaling, and decreases levels of cyclin D1. Topical application of RTA 408 activates Nrf2 and provides cytoprotective effects. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-(2-cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoro-propanamide, Omaveloxolone |
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| Gene, Accession, CAS # | CAS: 1474034-05-3 |
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| Catalog # | LS-H9778 |
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| Price | |
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| Order / More Info | RTA 408 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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