| 产品详情 |
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| Product Name | Recombinant Mouse NACHT, LRR and PYD domains-containing protein 3 (NIrp3), partial |
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| Description | 1-153aa; Partial. MW: 34.16kD. Purity >90% as determined by SDS-PAGE. May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA (By similarity). Activates caspase-1 as part of the NALP3 inflammasome complex in response to a number of triggers including bacterial or viral infe |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Cold autoinflammatory syndrome 1 protein homolog; Cryopyrin; Mast cell maturation-associated-inducible protein 1; PYRIN-containing APAF1-like protein 1] |
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| Gene, Accession, CAS # | Nlrp3, Gene ID: 216799, Accession: NP_665826.1 |
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| Catalog # | MBS1448454 |
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| Order / More Info | Recombinant Mouse NACHT, LRR and PYD domains-containing protein 3 (NIrp3), partial from MYBIOSOURCE INC. |
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| Product Specific References | Induction of PYPAF1 during in vitro maturation of mouse mast cells.Kikuchi-Yanoshita R., Taketomi Y., Koga K., Sugiki T., Atsumi Y., Saito T., Ishii S., Hisada M., Suzuki-Nishimura T., Uchida M.K., Moon T.-C., Chang H.-W., Sawada M., Inagaki N., Nagai H., Murakami M., Kudo I.J. Biochem. 134:699-709(2003) |
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