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| Product Name | MDMX Inhibitor, NSC207895 |
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| Description | Purity ~98% (HPLC). A cell-permeable benzofuroxan compound that is shown to suppress MDMX mRNA and protein expression and act as a p53 activator. Elevates p21, PUMA, BAX and PIG3 expression levels, blocks p53 degradation and induces apoptosis in MCF-7 cells at 5uM. Additively enhances p53 activation in combination with MDM2 Antagonist, Nutlin-3, Racemic and reduces MCF-7 cell survial. MDMX Antagonist, SJ-172550 is also available. Formula: C11H13N5O4 Solubility: DMSO Molecular Weight: 279.3 |
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| Size | 10mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | MDMX Inhibitor, NSC207895 (XI-006, 7-(4-Methylpiperazin-1-yl)-4-nitro-2,1,3-benzoxadiazole-1-oxide, 7-(4-Methylpiperazin-1-yl)-4-nitro-1-oxido-2,1,3-benzoxadiazol-1-ium) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217538 |
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| Order / More Info | MDMX Inhibitor, NSC207895 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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