| 产品详情 |
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| Product Name | GSK-1702934A |
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| Description | Purity >98% by TLC. GSK1702934A is a TRPC3 activator. In whole-cell patch-clamp experiments in HEK293 cells transduced with recombinant human TRPC3 or TRPC6, GSK-1702934A activated the TRPC3 and TRPC6 current with EC50 of 0.08 mM and 0.44 mM respectively. In the rat cardiomyocyte-like cell line H9C2 GSK-1702934A (1mM) activated TRPC6-like current and was completely blocked by GSK-417651A. It transiently increased the perfusion pressure of isolated rat heart retrogradely perfused via aortic cannulation at 1mM. Induces pro-arrhythmic and inotropic effects in TRPC3-overexpressing monocytes. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-(1-(5,6,7,8-Tetrahydro=4H-cyclohepta[b]thiophene-2-carbonyl)piperidin-4-yl)-1H-benzo[d]-imidazole-2(3H)-one |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | LS-H14693 |
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| Price | |
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| Order / More Info | GSK-1702934A from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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