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| Product Name | Recombinant Calloselasma rhodostoma Snaclec rhodocytin subunit alpha |
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| Description | 1-136. Full length. MW: 17.8kD. Purity >90% as determined by SDS-PAGE. Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLC-gamma-2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha-2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is cont |
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| Size | 0.01 mg (E-Coli), 0.01 mg (Yeast), 0.05 mg (E-Coli), 0.05 mg (Yeast), 0.1 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Aggretin alpha chain; Rhodoaggretin subunit alpha] |
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| Gene, Accession, CAS # | SLYA_CALRH, Accession: Q9I841 |
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| Catalog # | MBS1478856 |
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| Order / More Info | Recombinant Calloselasma rhodostoma Snaclec rhodocytin subunit alpha from MYBIOSOURCE INC. |
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| Product Specific References | Molecular cloning and sequence analysis of aggretin, a collagen-like platelet aggregation inducer.Chung C.-H., Au L.-C., Huang T.-F.Biochem. Biophys. Res. Commun. 263:723-727(1999) |
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