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| Product Name | Recombinant Calloselasma rhodostoma Snaclec rhodocytin subunit beta |
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| Description | 24-146aa; Full Length. MW: 16.37kD. Purity >90% as determined by SDS-PAGE. Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLCgamma2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is con |
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| Size | 0.01 mg (E-Coli), 0.01 mg (Yeast), 0.05 mg (E-Coli), 0.05 mg (Yeast), 0.1 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Aggretin beta chain; Rhodoaggretin subunit beta] |
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| Gene, Accession, CAS # | SLYB_CALRH, Accession: Q9I840.1 |
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| Catalog # | MBS1413379 |
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| Order / More Info | Recombinant Calloselasma rhodostoma Snaclec rhodocytin subunit beta from MYBIOSOURCE INC. |
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| Product Specific References | Molecular cloning and sequence analysis of aggretin, a collagen-like platelet aggregation inducer.Chung C.-H., Au L.-C., Huang T.-F.Biochem. Biophys. Res. Commun. 263:723-727(1999) |
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