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| Product Name | Trastuzumab (Herceptin®) BioAssay™ ELISA Kit |
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| Description | Trastuzumab (Herceptin®) is a humanized monoclonal antibody used in the treatment of HER2-positive cancers. Trastuzumab binds to domain IV of the extracellular domain of the HER2/neu receptor. Cells treated with Trastuzumab undergo cell cycle arrest during the G1 phase. It has been suggested that trastuzumab does not alter HER-2 expression, but decreases activation of AKT. Sample Type: Serum and plasma Intended Use: The Trastuzumab BioAssay™ ELISA kit is designed to measure trastuzumab with high specificity and enhanced sensitivity. The assay design utilizes a pair of antibodies that allows the detection of the whole trastuzumab molecule in biological matrices. Sensitivity: 1.25ng/ml Recovery: 1000ng/mL of Trastuzumab was spiked in 10 lots of human serum. Recovery ranges are from 91-117% with an average recovery of 106%. Precision: Intra-assay CV: <10% Inter-assay CV: <10%. Specificity: hIgG1, Rituximab, and Infliximab prepared at 250ng/mL were assayed and exhibited no cross-reactivity |
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| Size | 96 tests |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 384868 |
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| Order / More Info | Trastuzumab (Herceptin®) BioAssay™ ELISA Kit from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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