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| Product Name | AM1172 |
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| Description | Purity >98%. Numerous analogs of arachidonoyl ethanolamide (AEA) potentiate its biological activity. This potentiation is ascribed either to inhibition of AEA reuptake into neurons, or inhibition of fatty acid amide hydrolase (FAAH) within the neurons. AM1172 is an endocannabinoid analog specifically designed to be a potent and selective inhibitor of AEA uptake that is resistant to FAAH hydrolysis. Structurally, AM1172 is the reversed isomer of AM404, constructed using arachidonyl amine; this may account for its metabolic stability. In mouse cortical neurons, AM1172 blocked the uptake of tritiated AEA with an EC50 of about 1.5 µM. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-5Z,8Z,11Z,14Z-eicosatetraenyl-4-hydroxy-benzamide |
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| Gene, Accession, CAS # | CAS: 251908-92-6 |
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| Catalog # | LS-H6491 |
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| Order / More Info | AM1172 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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