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| Product Name | Tumor Necrosis Factor Soluble Receptor II (TNFsR-II) BioAssay™ ELISA Kit (Mouse) |
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| Description | This protein is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. Sample Type: Serum, plasma, tissue homogenates Intended Use: For the quantitative determination of mouse tumor necrosis factor soluble receptor II(TNFsR-II) concentrations in serum, plasma, tissue homogenates. Sensitivity: 1.6pg/ml Range: 7.8125-500pg/ml Specificity: This assay has high sensitivity and excellent specificity for detection of mouse TNFsR- II. No significant cross-reactivit |
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| Size | 48 tests, 96 tests, 24 tests |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 351731 |
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| Order / More Info | Tumor Necrosis Factor Soluble Receptor II (TNFsR-II) BioAssay™ ELISA Kit (Mouse) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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