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| Product Name | Tumor Necrosis Factor soluble Receptor I (TNFsR-I) BioAssay™ ELISA Kit (Mouse) |
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| Description | This protein is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease. Sample Type: Serum, plasma, tissue homogenates Intended Use: For the quantitative determination of mouse tumor necrosis factor soluble receptor I (TNFsR-I) concentrations in serum, plasma and tissue homogenates. Sensitivity: 1.261pg/ml Range: 15.625-1000pg/ml Specificity: This assay has high sensitivity |
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| Size | 48 tests, 96 tests, 24 tests |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: P25118 |
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| Catalog # | 351730 |
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| Order / More Info | Tumor Necrosis Factor soluble Receptor I (TNFsR-I) BioAssay™ ELISA Kit (Mouse) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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