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| Product Name | Recombinant Human von Willebrand factor |
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| Description | 1-273. MW: 46.2kD. Purity >90% as determined by SDS-PAGE. Important in the maintenance of hostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from prature clearance from plasma. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [von Willebrand antigen II] |
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| Gene, Accession, CAS # | VWF, Gene ID: 7450, Accession: NP_000543.2 |
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| Catalog # | MBS955451 |
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| Order / More Info | Recombinant Human von Willebrand factor from MYBIOSOURCE INC. |
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| Product Specific References | Nucleotide sequence of pre-pro-von Willebrand factor cDNA.Bonthron D., Orr E.C., Mitsock L.M., Ginsburg D., Handin R.I., Orkin S.H.Nucleic Acids Res. 14:7125-7128(1986) Structure of the gene for human von Willebrand factor.Mancuso D.J., Tuley E.A., Westfield L.A., Worrall N.K., Shelton-Inloes B.B., Sorace J.M., Alevy Y.G., Sadler J.E.J. Biol. Chem. 264:19514-19527(1989) The finished DNA sequence of human chromosome 12.Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S |
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