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| Product Name | PAK1/CDC42, Recombinant, Human, GST-Tag (p21-Activated Kinases, PAKalpha, MGC130000, MGC130001) |
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| Description | Purified (~70-90%). PAK1 is a member of the p21-activated kinases (PAKs) which have been implicated in the regulation of cell morphology, motility and transformation. These serine/threonine kinases are activated by and are effectors of small GTPases, CDC42 and RAC. PAK1 belongs to the Group I PAKs which also includes PAK2 and PAK3. PAK1 is a key regulator of the actin cytoskeleton, adhesion and cell motility. Inactive dimeric PAK1 is mainly cytosolic and interaction with the activators Cdc42-GTP and Rac1-GTP stimulates the kinase at the sites of cellular protrusions forming adhesions to the extracellular matrix. Source: Recombinant protein corresponding to human PAK1/CDC42, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~96kD Specific Activity: 46nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_002576 |
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| Catalog # | 500335 |
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| Order / More Info | PAK1/CDC42, Recombinant, Human, GST-Tag (p21-Activated Kinases, PAKalpha, MGC130000, MGC130001) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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