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| Product Name | FHIT, 1-147aa, Human, His tag, E Coli |
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| Description | MW: 17.9 kDa (155aa), confirmed by MALDI-TOF. Purity >95% by SDS-PAGE. FHIT (fragile histidine triad) is an enzyme that cleaves adenosine 5' PPP 5' A to yield AMP and ADP. FHIT gene encompasses the common fragile site FRA3B on chromosome 3. Alterations and deletions of the FHIT gene are strongly linked to the genesis and establishment of human tumors of the lung, cervix, breast, colon, stomach and pancreas. In normal cells, FHIT may act as a tumor suppressor. This protein physically associates w |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Fragile histidine triad protein; Bis (5'-adenosyl)-triphosphatase; AP3Aase; Fragile histidine triad protein AP3A hydrolase; AP3A hydrolase fragile site 3p14.2; Bis 5' adenosyl triphosphatase; Diadenosine 5' 5''' P1 P3 triphosphate hydrolase; Dinucleosidetriphosphatase; FRA 3B; FRA3B; Fragile histidine triad; Fragile histidine triad gene; Fragile histidine triad protein; Tumor suppressor protein.] |
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| Gene, Accession, CAS # | FHIT, Gene ID: 2272, Accession: NP_002003 |
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| Catalog # | MBS203463 |
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| Order / More Info | FHIT, 1-147aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Kmiec Z., et al. (2009) J Physiol Pharmacol. 60 (4):63-70.; Ahmad F., et al. (2010) J Cancer Res Clin Oncol. 136 (3):333-50.; |
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