| 产品详情 |
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| Product Name | Cardiotrophin-1, Recombinant, Mouse (CT-1) |
| Description | Purity ~98% (SDS-PAGE). CT-1 is a member of the IL-6 family of cytokines which also includes LIF, CNTF, OSM (Oncostatin M), IL-11, IL-6 and possibly NT-1/ BSF-3. CT-1 is a pleiotropic cytokine which is expressed in various tissues including the adult heart, skeletal muscle, ovary, colon, prostate and fetal lung and signals through the LIF receptor and the gp130 receptor subunit. CT-1 has the ability to induce cardiac myocyte hypertrophy, and enhances the survival of cardiomyocyte and different neuronal populations. Biologically active human CT-1 is synthesized as a 201aa polypeptide lacking a hydrophobic N-terminal secretion signal sequence. Source: Recombinant protein corresponding to 202aa residues from mouse Cardiotrophin-1, expressed in E. coli. Molecular Weight: ~21.3kD Biological Activity: Determined by its ability to stimulate the proliferation of human TF-1 cells. The expected ED50 is ≤1.0ng/ml, corresponding to a specific activity of ≥1x10e6units/mg. Endotoxin: <0.1ng/ug of pr |
| Size | 10ug |
| Concentration | n/a |
| Applications | n/a |
| Other Names | CT-1 |
| Gene, Accession, CAS # | CT1, Gene ID: 13019, SwissProt: Q60753 |
| Catalog # | 219520 |
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| Order / More Info | Cardiotrophin-1, Recombinant, Mouse (CT-1) from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
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