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| Product Name | SQSTM1, 1-356aa, Human, His tag, E Coli |
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| Description | MW: 39.7 kDa (364aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher). Purity >90% by SDS-PAGE. SQSTM1 is an adapter protein which binds ubiquitin and regulates signaling cascades through ubiquitination. It may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1 and play a role in titin/TTN downstream signaling in muscle cells. This protein also may be involved in cell differentiation, apoptosis, immune response and regulation of K+ |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Sequestosome 1; A170; OSIL; p60; p62; p62B; PDB3; ZIP3; Sequestosome 1 EBI 3 associated protein of 60 kDa; ZIP; ZIP 3; EBI3 associated protein of 60 kDa; EBIAP; MGC127197; ORCA.M530; OSF-6; Osi; Oxidative stress induced like; Paget disease of bone 3; PDB 3; Phosphotyrosine independent ligand for the Lck SH2 domain of 62 kDa; Phosphotyrosine independent ligand for the Lck SH2 domain p62; PKC-zeta-interacting protein; Protein kinase C-zeta-interacting protein; SQSTM 1; STAP; STONE14; ubiquitin bi |
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| Gene, Accession, CAS # | SQSTM1, Gene ID: 8878, Accession: NP_001135771 |
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| Catalog # | MBS203612 |
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| Order / More Info | SQSTM1, 1-356aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Falchetti A., et al. (2004) J Bone Miner Res. 19 (6):1013-7. |
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