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| Product Name | Jumonji HDM Inhibitor, JIB-04 |
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| Description | MW: 308.76. Purity ≥98% by HPLC. Background: JIB-04 (E-isomer) is a potent, cell-permeable inhibitor of Jumonji histone demethylases in vitro and in vivo. (In vitro IC?? values are 230, 340, 435, 445, 855 and 1100 nM for JARID1A, JMJD2E, JMJD2B, JMJD2A, JMJD3 and JMJD2C respectively). JIB-04 is not a competitive inhibitor of alpha-ketoglutarate ; it selectively inhibits viability of several human cancer cell lines with little toxicity towards normal cells, and also diminishes tumor growth in |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [5-Chloro-2-[(E)-2-[phenyl(pyridin-2?-yl)methylidene]hydrazin-1-yl]pyridine; NSC693627] |
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| Gene, Accession, CAS # | CAS: 199596-05-9 |
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| Catalog # | MBS842082 |
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| Order / More Info | Jumonji HDM Inhibitor, JIB-04 from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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