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| Product Name | TRIAP1, Recombinant, Human, aa1-76, GST-Tag (TP53-regulated Inhibitor of Apoptosis 1) |
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| Description | Purity ~90% (SDS-PAGE). Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes (in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo). Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis. Source: Recombinant protein corresponding to aa1-76 from human TRIAP1, fused to GST-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~35.8kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Protein 15E1.1 WF-1 p53-inducible cell-survival factor |
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| Gene, Accession, CAS # | SwissProt: O43715 |
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| Catalog # | 375671 |
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| Order / More Info | TRIAP1, Recombinant, Human, aa1-76, GST-Tag (TP53-regulated Inhibitor of Apoptosis 1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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